المجلد السادس

العدد الثاني عشر لشهر ديسمبر 2021

رجوع

تحميل البحث

full-text

الملخص:

الملخص الارتيميا (Artemia) أحد الأنواع البحرية التي تستخدم في مناطق محدودة من العالم، ونظرًا للاستخدام الشائع لها في الجنوب الليبي كغذاء وعلاج للأمراض المعوية دون الاعتماد على أساس علمي، وفي نفس الوقت تزايد مقاومة البكتيريا للمضادات الحيوية أجريت هذه الدراسة بهدف: دراسة مدى تأثير المنقوع والمستخلص المائي والعضوي كمضاد بكتيري على بعض الأنواع البكتيرية المسببة للأمراض المعوية واختبار التأثير التآزري مع المضادات الحيوية، تم جمع عينات الدود وتحضير منقوع، ومستخلص مائي (ساخن وبارد)، ومستخلص عضوي، جميعها بتراكيز2، و5، و10، و20, و40%، بينت النتائج أن لمنقوع الدود (بارد وساخن) تأثير تثبيطي ضد S. aureus ATCC 6538P والساخن بتركيزات 10، و20، و40% ضد E.coli ATCC10536، وأن للمستخلص المائي (ساخن وبارد) تأثير بتركيز 20 و40% ضد E.coli ATCC10536 وS.aureus على التوالي، والمستخلص العضوي ضد E.coli ATCC10536، أشارت النتائج إلى زيادة حساسية الأنواع البكتيرية ماعدا E.coli (العزلة السريرية) للمضاد Neomycim المشبع بالمستخلص البارد بالتراكيز المدروسة وإضافة لذلك، زادت حساسية S. typhimurium ATCC 14028 وE.coli ATCC10536 و S. aureus ATCC 6538P للمضاد Streptomycin المشبع بالمستخلص الساخن، وحساسية S. typhimurium ATCC 14028 و E.coli ATCC10536 للمضاد Kanamycin وحساسية وE.coli ATCC10536 وS. aureus ATCC 6538P للمضاد Amikacin، أما العضوي زاد من حساسية E.coli للمضاد Kanamycin المشبع بجميع التراكيز و E.coli السريرية و S. aureus ATCC 6538P للمضاد Neomycim. أظهر المضاد Neomycim أفضل تأثير تآزري ضد جميع الأنواع بجميع التراكيز للمستخلص المائي (بارد وساخن) والعضوي.

كلمات افتتاحية: الأرتيميا، الإصابات المعوية، المضادات الحيوية، البكتيريا، العلاجات البحرية، ,Antibiotic intestinal disease

Abstract:

Artemia is one of the marin species, and it is used in limited parts of the world. Due to its common use in the southern Libya as food and drug for intestinal diseases without scientific evidences, and at the same time there is an increasing bacterial resistance to antibiotics, this study was conducted to investigate the effect of soaked, aqueous and organic extract (according to conventional doses of Artemia) on some enteric pathogenic bacteria. Samples of Adood (Artemia) were collected, and the extracts were prepared by soaking, aqueous (hot and cold) extract and ethanol extract at concentrations of 2, 5, 10, 20, 40%. The results showed that soaked (cold and hot) inhibited S. aureus ATCC 6538P, and hot with 10, 20, 40% inhibited E.coli ATCC10536. Aqueous extract 20% inhibited E.coli, and 40% inhibited S. aureus ATCC 6538P. The organic extract inhibited E.coli ATCC10536 only. Saturated antibiotics with cold aqueous extract indicated an increase in the sensitivity of bacterial species, except clinical E.coli for saturated Neomycim at all the concentrations. In addition, it increased the sensitivity of S. typhimurium ATCC 14028, E.coli ATCC10536 and S. aureus ATCC 6538P for saturated Streptomycin with hot. S. typhimurium ATCC 14028 and E.coli ATCC10536 for Kanamycin and E.coli ATCC10536 and S. aureus ATCC 6538P for Amikacin. While organic extract increased the sensitivity of E.coli to the saturated Kanamycin with all the concentrations and the clinical E.coli and S. aureus ATCC 6538P for Neomycim. The best synergistic effects against all species with all the concentrations of aqueous extract (cold and hot) and organic was noted with Neomycim.

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